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Glyoxylate and alanine can also be converted to glycine and pyruvate, respectively, via the action of the vitamin B6-dependent enzyme, alanineglyoxylate and serinepyruvate aminotransferase (encoded by the AGXT gene)

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Alprostadil's risks are predominantly local (injection site pain, priapism, fibrosis) while PT-141's risks are predominantly systemic (nausea, BP changes)

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