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Genetic ablation of DPP9 reverses this resistance in vivo and in organoids, suggesting that small-molecule disruption of the DPP9KEAP1 interface could resensitize NRF2-hyperactive tumors to ferroptosis-inducing therapy

Efficacy Assessment Subcommittee of the American College of Physicians

4 In addition to pain and pain dysregulation, patients suffering from fibromyalgia often experience muscle and joint stiffness, sleep disturbances, and cognitive and psychiatric ailments, leading to significant decreases in quality of life

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