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Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell

Interestingly, a positive feedback loop could also be established between p38 MAPK and oxidant species, since this kinase can promote the increase in ROS levels ( Another relevant pathway involved in the regulation of the SASP is the cyclic GMPAMP synthasestimulator of interferon genes (cGASSTING) pathway

Metformin and pioglitazone exerted their beneficial effects without adverse metabolic effects, indicated by no changes in body weight during or after the treatment

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