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& Sarpong, R
Unlike direct GPX4 inhibition, which remains difficult to deploy in vivo owing to bioavailability and systemic toxicity concerns, targeting enzymes that sustain the reduced CoQ 10 (CoQ 10 H 2 , ubiquinol) pool may provide a more tractable and context-selective strategy to lower the ferroptotic threshold in tumors
doi: 10.1080/1040841X.2020.1800587 205 MaGChenZLiZXiaoX
Identifying the trajectory of malignant cells could reveal the key molecules and mechanisms that may drive the carcinogenesis of epithelial cells
