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doi: 10.1016/0014-4800(90)90070-T
Whole-genome sequence analysis along with linkage analysis has shown homozygous or compound heterozygous mutations in COQ2 in two of the six multiplex Japanese families with MSA [110]
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However, ongoing technical developments in HRMS combined with powerful data acquisition and processing may enable qualitative and quantitative analysis in the future (Vidal et al
