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Description
They are the major mediators of bronchoconstriction in asthma, acting through CysLT1 and CysLT2 receptors to cause airway smooth muscle contraction, increased vascular permeability, and mucus secretion
Clin Expl Allergy
Wnt5a activats Wnt/PCP pathway, upregulating Ras-related C3 botulinum toxin substrate 1(Rac), which can activate JNK, thus aggravating IR in adipose tissue
FPB wrote the paper with the assistance of all authors, who have read and approved the final manuscript
