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Moreover, as lysosomal function is essential for mitophagy, impairment in the fusion of lysosomes with autophagosomes-containing mitochondria may compromise the clearance of dysfunctional mitochondria, resulting in exacerbated APAP hepatotoxicity

doi: 10.1016/j.arr.2023.101978 82 KumariS.KumaranS.GoyalV.SharmaR

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In parallel, antigen presentationrelated genes, including Cd74 and Tap1, were upregulated, supporting improved antigen processing capacity