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However, tumor cells can remodel TME by several means, including increased immunosuppressive population, reduced infiltration of tumor-inhibitory immune cells, reduced presentation of tumor antigens on MHC molecules, and more, allowing them to evade the immune system ( Figure 3F )
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Lycopene is a more potent antioxidant than betacarotene, and it can prevent free radical damage and programmed cell death of macrophages
