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Its unique research profile makes DSIP useful for studies focused on neuropeptide biology, signaling network characterization, and mechanistic analysis of peptide-mediated regulatory processes.

Friction from heavy jewelry, harsh scrubbing (which most people do to "clean" the neck), or allergic reactions to perfumes (Berloque dermatitis) can cause the melanocytes to overproduce pigment

Sci Rep 10(1):17401

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