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Higher levels of inactive MGP in patients were associated with an increase in arterial stiffness as determined by pulse-wave velocity, which was one of the early indicators of vascular dysfunction (137)

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Holmes GP, Kaplan JE, Gantz NM, Komaroff AL, Schonberger LB, Straus SE, et al

A receptor that binds AGE is present in the plasma membrane of numerous cell types including immune cells, vascular endothelial cells, and smooth muscle cells
