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This aligns with findings in human induced pluripotent stem cell-derived sensory neurons (iPSC-SNs), where retigabine and the specific Kv7.2/3 activator ICA-110381 hyperpolarized the resting membrane potential, increased action potential threshold, and robustly inhibited neuronal firing, whereas the Kv7.1-specific activator ML277 had no effect, confirming the critical role of Kv7.2/3 subunits in regulating human sensory neuron excitability (Estacion et al., 2023)

The principal antioxidant mechanisms of vitamin D are reviewed in Figure 2

While this study found that standard tea may reduce the risk of vitiligo by regulating oxidative stress at the genetic level, it is important to acknowledge the antioxidant capacity of other teas