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During parturition, PGE2 and PGF2 promote cervical ripening and uterine contraction, and COX-2 expression in the fetal membranes increases dramatically in the hours preceding labor

Nat Metab 2:817828 Hultstrm M, Amorim de Paula C, Fontes AP, M., Porcelli, S., Bellistri, G., Pugliese, L., et al (2015) Commentaries on Viewpoint: Can elite athletes benefit from dietary nitrate supplementation

doi: 10.1001/archinte.165.7.742

This is supported by the findings of a study conducted in patients with respiratory disorders which showed that, after an oral administration of 100 mg of 35 S-labelled NAC, plasma radioactivity concentrations remained high after 24 h, and that approximately 22% of radioactivity (range 1338%) was excreted in urine after 24 h [3]