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140 In vitro and in vivo (mouse) studies have investigated the combination of gamma-tocotrienols with gemcitabine in pancreatic cancer and found an anti-tumor benefit, while a phase 1 trial on pancreatic cancer patients showed that administering vitamin E supplementation (as 2001,600 mg delta-tocotrienol daily) for two weeks prior to surgery resulted in apoptotic cell death of cancer cells

Psychopharmacology (Berl) 109 : 433438 Overmier JB, Seligman MEP

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