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BCAAs provide the primary nitrogen source for glutamate synthesis, which in turn enables ammonia detoxification through glutamine synthetase [40]

Lancet Oncol 16(4):e173-80, 2015
In particular, the reduction of one of the GABA-synthesizing enzymes, the 67-kDa isoform of glutamate decarboxylase (GAD67), has garnered interest among researchers because of its role in the formation of -oscillations and its potential involvement in the cognitive dysfunction observed in schizophrenia
