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McGuinnessMBKarahaliosASimpsonJAGuymerRHRobmanLDHodgeAMet al

This enzymatic degradation substantially reduces the amount of intact glutathione that reaches the bloodstream, limiting the therapeutic concentration available to cells and tissues throughout the body

Ackerman, D

Examples for redoxactive IMS enzymes are the subunits of the respiratory chain (complexes III and IV, and the NADH dehydrogenases Nde1 and Nde2), and antioxidant enzymes like superoxide dismutase 1 (Sod1) and cytochrome c peroxidase (Ccp1)