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This study identified four biomarkers, APEX1, ECHDC2, NME3, and PUS1, through bioinformatics analysis and verified by RT-qPCR

However, this virus can also cause serious illness in immune-compromised individuals, elderly patients, and in those with certain preexisting health conditions, such as hypertension, diabetes, and cardiovascular disease.1 It takes approximately 7 days to develop computed tomography (CT)-confirmed pneumonia (COVID-19) from the onset symptoms, such as fever or dry cough, and another 2 days to progress to acute respiratory distress syndrome (ARDS).2 ARDS is the major cause of death for COVID-19 patients and is associated with dysregulated host immune responses following viral infection

Nevertheless, in neuronal replacement and axonal regeneration, newly generated axons must signal the host environment to acquire de novo myelination in a pathological condition

Current critical care management of TBI focuses on general intensive care support and specific neurocritical care interventions to minimize further damage to the brain by preventing hypoxia, hypotension and hypoventilation