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Upon bile acid activation, hepatic FXR induces expression of small heterodimer partner (SHP), which suppresses CYP7A1 and CYP8B1 gene transcription, thereby reducing bile acid synthesis (68)
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Abstract Cerebral ischemia, a leading cause of neurological disability and death, is characterized by reduced cerebral blood flow that induces hypoxia, neuronal injury, and irreversible brain damage
Results Of the seven reported cases of warfarin-durian interactions, all individuals experienced increased INR following durian consumption
