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Gastrointestinal symptoms Tongue soreness, appetite loss, and constipation have also been associated with vitamin B 12 deficiency

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To put it in context, nicotinamide has shown signs of liver toxicity only at doses around 3,000 mg per day or higher

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Zaman Javaheri, M.D

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But if you take B12 supplements, you risk ingesting more B12 than you actually need

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