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Gastrointestinal symptoms Tongue soreness, appetite loss, and constipation have also been associated with vitamin B 12 deficiency

To put it in context, nicotinamide has shown signs of liver toxicity only at doses around 3,000 mg per day or higher

Zaman Javaheri, M.D

But if you take B12 supplements, you risk ingesting more B12 than you actually need
