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Description
While AOD-9604 does not stimulate cell proliferation (no IGF-1 elevation), the precautionary principle applies for active malignancies
Its core pathological feature is excessive accumulation of adipose tissue, accompanied by abnormal proliferation, differentiation, and metabolic dysfunction of adipocytes, which in turn induce a series of complications including insulin resistance, nonalcoholic fatty liver disease, and cardiovascular diseases
doi: 10.2105/AJPH.2015.302773
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