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Evidence suggests that curcumin may modulate pain sensations via decreasing levels of a free radical called nitric oxide and suppressing the inflammatory mediator TNF- (Sharma 2006)
Another study showed that at 7,500 mg/day, there is a slight blood pressure-lowering effect.[ref] A 2021 study on adults prescribed to take choline (alpha-GPC) found a correlation between increased stroke risk and taking alpha-GPC
For changes in body composition, the determining factors are usually energy balance, training and adherence
