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In humans, two enzymatic reactions are dependent on vitamin B 12 methylmalonyl coenzyme A mutase (MUT) reaction and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) reaction (Fig 2)
Recent research into Long COVID and ME/CFS suggests that this prolonged immune activation can severely deplete the body's stores of essential nutrients, including Vitamin B12 and Folate
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