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Under physiological conditions, it is either remethylated to methionine or irreversibly metabolised through the transsulphuration pathway

(3) Case 3: Morphology resembled focal nodular hyperplasia (slight nodularity, fibrous bands, ductular reaction), serum amyloid-associated protein positive, and glutamine synthetase pseudo map-like

6.3 ALA Alpha-lipoic acid (ALA) is a disulfide compound with unique biochemical properties: it is both water- and fat-soluble, enabling it to act throughout the cell, and it can counteract excessive ROS induced by chronic hypoxia by neutralizing free radicals, chelating metal ions, and regenerating other antioxidant substances (such as vitamins C and E and glutathione)

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