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Then, a grid was generated by taking the standard ligand bound to the co-crystallized protein as the center, and the grid coordinates were noted

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As such, biosensors or wearables that can continuously assess plasma BDNF levels and stress biomarker levels, along with cognitive performance will emerge as an innovative method to identify opportunity for real-time adjustments to the therapeutic intervention that may maintain therapeutic efficacy [330]

Thus, autophagic flux is an important factor in monitoring the formation and degradation of autophagosomes (Klionsky et al., 2016
