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The FOLR1 gene represents one member of a family of folate receptor genes that are clustered at the 11q13.4 locus

doi: 10.1016/j.molcel.2016.06.030

Sirolimus: its discovery, biological properties, and mechanism of action

The senolytic demonstrates preferential elimination of transforming growth factor- (TGF-)-induced myofibroblasts while sparing normal fibroblasts, showing selectivity for pathological senescent cells driving fibrosis