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Sun L, Wang H, Wang Z, He S, Chen S, Liao D, et al

In this study, we examine how diminished GPX4 function may be a critical event in triggering oxytosis/ferroptosis to perpetuate or initiate the neurodegenerative diseases and assess the possible therapeutic importance of oxytosis/ferroptosis in neurodegenerative disorders

Targeted genetic silencing of SREBP2 in DCs, as well as its pharmacologic inhibition, enhanced antitumor CD8 + T cell activation and inhibited melanoma progression

PMID: 39300112 Sci Signal Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer