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For advanced cases, deep brain stimulation targeting the subthalamic nucleus effectively reduces motor fluctuations by up to 60% (3639), though it carries procedural risks including infection (35%) and cognitive adverse effects (1015%) [266, 267]

doi: 10.3389/fcimb.2015.00036 41 MoreraDRoherNRibasLBalaschJCDoateCCallolAet al

J Clin Exp Pharmacol, 9(262), 2161-1459

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