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In the absence of CUP-5, the rate of YP170 and LMP-1 transport to lysosomes is reduced leading to the progressive enlargement of yolk granules (Fig

Paradigms such as foot shockinduced fear conditioning and fear-potentiated startle are widely used to model these features of PTSD and have been pharmacologically validated for translational relevance 40

For the same reason, spironolactone should not be used during pregnancy