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The use of desferrioxamine, an iron chelator, confirmed that iron was directly responsible for lesion growth (35)

doi: 10.1038/ismej.2012.6 211

GluN2C subunit is critical to normal cortical neuronal oscillations Due to their unique biophysical properties such as reduced voltage-dependency due to a lower sensitivity to Mg 2+ -blockade as well as lack of desensitization 17 , GluN2Ccontaining receptors may be active without the requirement for prior depolarization and via spillover glutamate thereby leading to tonic activity, which can impact neuronal oscillations

Rocas P, Fernndez Y, Garca-Aranda N, Foradada L, Calvo P, Avils P, et al