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This has been demonstrated by the observation that the glutathione conjugate of the anti-cancer drug cisplatin, is enzymatically converted to the corresponding cysteinylglycine compound [59]

In conclusion, this study has shown that GGC can decrease apoptosis, oxidative stress and inflammation in human astrocytes and protect astrocytes from oligomeric A 40 -mediated cytotoxicity cellular GSH depletion

Measurement of Protein Content For the determination of protein content, the Lowry method [33], was employed

Combined treatment of l-carnitine and metformin significantly decreased the number of squares crossed in OFT as compared to l-carnitine-alone-treated diabetic rats and significantly increased the time spent at the center of the open field as compared to untreated diabetic rats and metformin-alone and l-carnitine-alone-treated diabetic rats