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It has been shown to reduce tau pathology in an animal model (Kontsekova et al., 2014), and it has been tested in a clinical trial(ADAMANT;NCT02579252) in phase 1 and phase 2 on Alzheimers patients

This study aims to test the hypothesis that the antioxidant effect of the synthetic tetrapeptide AEDG (Ala-Glu-Asp-Gly, Epitalon) improves the delayed healing process associated with hyperglycemia in DR, using a high glucose (HG)-injured human retinal pigment epithelial cell line (ARPE-19)

Infant with fetal hydantoin syndrome