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In previous studies, excess extracellular glutamate suppresses the antiporter activity of system x C - therefore inhibits the uptake of cyst(e)ine and sensitizes cells to ferroptosis 1

Al-Massri KF, Ahmed LA, El-Abhar HS (2018) Pregabalin and lacosamide ameliorate paclitaxel-induced peripheral neuropathy via inhibition of JAK/STAT signaling pathway and Notch-1 receptor

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Protective effects of a vitamin B12 analog, methylcobalamin, against glutamate cytotoxicity in cultured cortical neurons
