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High VEGF expression during angiogenesis in breast cancer decreases CD8 T-cell levels via the HMG-bOX ( TOX ) pathway, thereby increasing tumor-cell tolerance to immunotherapy 70 ( Figure 3F )

Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer

et al., Saccharomyces boulardii , likewise exhibit barrier-restorative and anti-inflammatory activity across formulations ( Summary data in Table 2 highlight shared patterns and genus-specific features of probiotic interventions: (1) Synergy across mechanisms is pervasive