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Due to inconsistent units of measurement across studies, the standardized mean difference (SMD) was adopted as the common effect size metric, with Hedges g used for small-sample correction (Lifeng Lin and Aloe, 2021)

It functions by interacting with specific high-affinity ligands, triggering a cascade of biological responses that researchers are eager to quantify
This gradual titration protocol begins at 50 mg daily to assess tolerance, as starting too high can produce adverse reactions such as insomnia, anxiety, or fatigue [4]
Growth-hormone and endocrine research references
