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Type III collagen is also cleared promptly and substituted with collagen type I fibers starting at the 14th day of treatment (i.e., improved load to failure correlate with the advanced collagen type I distribution) (Figure 10e,f,k,l and Figure 11e,f)

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Recordings were obtained using a Multiclamp 700B amplifier (Molecular Devices, Sunnyvale, CA), Analog signals were low-pass Bessel filtered at 2 kHz, digitized at 10 kHz through a Digidata 144 OA interface (Molecular Devices), and stored in a computer using Clampex 10.2 software (Molecular Devices)