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At the segment level, Phase II's above-average growth is driven by two parallel trends: the expansion of hybrid designs into exploratory efficacy trials where ePRO and wearable endpoints can be co-validated alongside conventional assessments, and the increasing use of Phase II studies as the proving ground for the technology stacks and home health service models that will be deployed in subsequent Phase III programs

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Carloni S., Bertocchi A., Mancinelli S., Bellini M., Erreni M., Borreca A., Braga D., Giugliano S., Mozzarelli A.M., Manganaro D., et al

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