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Increased infiltration and activation of mast cells [162,163,164,165], together with elevated levels of mast cell mediators, including histamine and proteases, but also relevant miRNAs and neurotrophins have been substantiated in DGBIs [166,167,168,169]

To reduce the likelihood of future epidemics, positive lifestyle changes (i.e., toward healthy eating habits) must be reflected since evidence indicates that slaughterhouse cooling chambers provide an optimum environment to preserve highly infectious viruses, like SARS-CoV-2, which further raises the need to talk about meat (368, 369)

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