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This trial, while not showing superiority of JTA-004 over placebo in the overall population, provides highly valuable insights into clinical trial design, placebo responses, and the potential need for better patient stratification in osteoarthritis research
This progress was also supported by the histological findings

Criteria 3, SpecificityHg appeared to be involved in multiple mechanism pathways and play a role in multiple metabolic risk factors
A.Fernandez-CalleP.VazquezA.Cabrera-ValdiviaF.CatalanM
