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NICE obesity guidance recommends evidence-based interventions including dietary change, physical activity, and licensed medications such as orlistat or semaglutide

The current evidence is based on its known biological mechanisms and promising results from animal studies on nerve injury, inflammation, and tissue repair

This was not the case during the implementation of the MDGs, where NorthSouth partnerships were most commonly developed from a Northern perspective, according to Northern priorities rather than attentive of Southern needs and views 39

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