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Furthermore, L-carnitine is reported to lower the threshold for seizures in some individuals, especially those with a history of seizures, but no evidence to support this alleged effect has been found [58]
Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function
Recent findings in these areas may guide the field towards novel targets for future therapeutic approaches in MS
In contrast, co-treatment with LC substantially mitigated these impacts
