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have shown that the delivery of GDNF-overexpressing MSCs (GDNF-MSCs) to the intact rat striatum elicited reduced microglial and astrocytic recruitment, suggesting improved biocompatibility [105]

This may be due to the addition of niosome to glutathione which allows more penetration, more absorption and in turn more efficacy

3 Although limited data supports the use of glutathione via the IV route for liver health, one study of glutathione 500mg per day in combination with pyridoxine HCl 50mg per day found supplementation not to significantly improve severity of liver cirrhosis

Here, it should be strongly emphasized that the research on the gut microbiome in CIPN is still at an exploratory stage, and potential therapeutic methods based on microbiota manipulation require further preclinical and clinical research