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Description
Disruption of SLC 25A1 function severely affects the synthesis of TCA intermediates, compromising ATP production, amino acid biosynthesis, fatty acid metabolism, and other essential biochemical processes

Wilcken et al, 1996)

These processes are regulated by more than 40 ATGs and multiple signaling pathways and proteins [70], the most notable of which are the mammalian target of rapamycin (mTOR) pathway, the AMP-activated protein kinase (AMPK) pathway, and the proteins Beclin-1 and LC3-II

References Epithalamin/Epithalon
