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It is not known if Wegovy will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people Do not use Wegovy if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Do not use Wegovy if: you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) you have had a serious allergic reaction to semaglutide or any of the ingredients in Wegovy injection or Wegovy tablets

doi: 10.1016/j.ijcard.2014.09.005

Notably, normal rats exhibited a superior sagittal sinus pressure of 24 to 27 mmHg and superior mesenteric pressure and portal pressure of 35 mmHg, which is similar to that of the inferior vena cava, although with values at least 1 mmHg higher in the portal vein

This results in fewer serious side effects, minimal disruption to endogenous hormone production, and lower risks to organs like the liver and heart