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While aminoguanidine has not been evaluated in diabetic CVD in clinical studies, a phase III randomized trial by Bolton et al
For example, the concept of low-risk neoplasms is seen as a measure to curb overdiagnosis and overtreatment in Western countries, but evidence-based assessments of benefits and harms specific to Japan remain undetermined

doi: 10.1038/nri3705 136 HenekaM

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