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Description
Recent studies reveal that a large subgroup of children with autism spectrum disorder (ASD) have FRAAs
Health 35 , 497506 (2019)
However, the kinetic patterns do not support a ping-pong mechanism and the nonenzymatic first reaction with a second order rate constant of 0.6 M 1 s 1 is too slow to explain the rapid turnover 3,12,14,15,30
Targeting of IGF-1R to block its signalling may be obtained by interference with ligand/receptor interactions, receptor synthesis and expression, receptor TK activity, or combinations of these strategies
