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Mechanism of selective anticancer activity of isothiocyanates relies on differences in DNA damage repair between cancer and healthy cells

In some cases, the cell can compensate for mitochondrial damage and refresh its mitochondrial network, whereas in other cases, the cell will clear the damaged mitochondria by mitophagy or cell death will occur

The SURMOUNT-1 trial showed average weight loss of 20.2 percent at 72 weeks on the highest dose, a figure that stunned the medical community when it was first published
