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The V-CNT group received bilateral 30 L saline (0.9% NaCl), while the SUPP group received bilateral 0.65 mg cyanocobalamin (Sigma Aldrich 47869) dissolved in 30 L saline (0.9% NaCl), providing a total dose of 1.30 mg vitamin B12 per mouse per week for 12 weeks
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Using hydrogen peroxide-induced senescent TM3 Leydig cells as an in vitro model, the study confirmed that FOXO4 maintains senescent Leydig cell viability and suppresses apoptosis

How Much Vitamin B12 Do You Need
