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Concurrently, a weakening of prefrontal inhibitory control over these limbic structures, mediated by dendritic atrophy and reduced connectivity, leads to a loss of topdown regulation, resulting in negative affective states, cognitive deficits, and the persistence of pain memory [85, 86, 87]

A randomized controlled study demonstrated that acupuncture combined with methylcobalamin is more effective in treating BIPN than methylcobalamin alone (Moore et al., 2020)

Each problem requires a different approach

demonstrated that the GPX4 inhibitor RSL3 selectively promotes ferroptosis in DCs (72)
