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159 Research has also shown that the binding of daratumumab to CD38 modifies cytoskeleton reorganization in MM cells by inducing a redistribution of CD38 antigens into polar aggregates that are released into the BM microenvironment

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Radiology 284:153160 van Rijn RM, Wassenaar M, Verhagen AP et al (2012) Computed tomography for the diagnosis of lumbar spinal pathology in adult patients with low back pain or sciatica: a diagnostic systematic review