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Description
Folate and betaine act on the DNA methylation pathway and increase the degree of methylation of the CpG binding proteins, leading to restoration of the Rett syndrome phenotypes in pre-clinical trials
Zhu M, Zheng Z, Huang J, Ma X, Huang C, Wu R, Li X, Liang Z, Deng F, Wu J
PubMed Frezza M, Centini G, Cammareri G, et al
Applying this scale to our patient, he meets the condition of erosive lesions involving 10-29% of the total body surface area, which gives a score of 1 and classifies it as a moderate disease
