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The evaluation and management of macrocytosis has been recently reviewed in American Family Physician ( Unlike hematologic manifestations, the specific mechanism by which vitamin B 12 deficiency affects the neurologic system is unknown

How semaglutide can affect B12 absorption As semaglutide works by slowing gastric emptying and promoting the feeling of satiety (reduced cravings) for weight loss, it may influence the bodys ability to absorb certain nutrients, including vitamin B12

Despite this, the ability of GLP-1 agonists to offer multiple therapeutic effects beyond their primary uses is drawing considerable interest from the medical community